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. 2013 Feb 8;8(2):e56273. doi: 10.1371/journal.pone.0056273

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© 2013 Shroff et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Serum Ang-1 levels (A) were significantly lower in pre-dialysis CKD patients compared with healthy controls. In dialysis patients Ang-1 levels were similar to values found in healthy controls. Similar levels of both circulating Ang-2 (B) and Ang-2/Ang-1 (C) were found in healthy children and those with pre-dialysis CKD, but these were significantly increased in the dialysis group.