Figure 8. Fluorescence microscope images of mouse bone marrow derived dendritic cells treated with (A) LPSiNPs or (B) FGK-LPSiNPs for 1.5 h at 37°C. (C) 30 min pretreatment of the bone marrow-derived dendritic cells (green) with free FGK45 inhibits uptake of FGK-LPSiNPs incubated with the cells for 1.5 h at 37°C. FGK-LPSiNPs were detected by their intrinsic visible/near-infrared photoluminescence (red, λex = 405 nm and λem = 700 nm). The scale bars are 40 µm. (D) Distribution of FGK-LPSiNPs bone marrow-derived dendritic cells after 1.5 h incubation at 37°C. The lysosomes are stained in green (LysoTracker; Invitrogen), the nucleus in blue and FGK-LPSiNPs in red. The scale bar is 10 µm. Reprinted and modified with permission from reference 116.