Table 1.
Subject Characteristics stratified by KL grade.
| WOMAC | |||||||
|---|---|---|---|---|---|---|---|
| Age (yrs) |
Height (cm) |
Weight (kg) |
BMI | Pain | Stiffness | Function | |
|
Controls (n=19) |
|||||||
| Mean | 39.10 | 172.50 | 70.79 | 23.47 | 3.26 | 1.63 | 6.79 |
| SD | 10.15 | 9.09 | 12.66 | 3.44 | 3.26 | 1.67 | 8.98 |
|
Mild OA (n=26) |
|||||||
| Mean | 52.27* | 170.04 | 75.28 | 26.00 | 3.19 | 1.88 | 10.42 |
| SD | 10.30 | 9.05 | 13.49 | 4.01 | 3.13 | 1.24 | 11.11 |
| p-value (vs. controls) |
<0.0001 | 0.087 | 0.948 | 0.578 | 0.300 | ||
|
Severe OA (n=18) |
|||||||
| Mean | 62.61*# | 166.58 | 80.89 | 29.33*# | 10.72*# | 4.67*# | 35.55*# |
| SD | 10.33 | 8.48 | 16.67 | 6.78 | 4.48 | 1.64 | 14.15 |
| p-value (vs. controls) |
<0.0001 | 0.0005 | <0.0001 | <0.0001 | <0.0001 | ||
| p-value (vs. mild OA) |
0.0017 | 0.028 | <0.0001 | <0.0001 | <0.0001 | ||
| ANOVA Prob>F |
<0.0001 | 0.137 | 0.106 | 0.002 | <0.0001 | <0.0001 | <0.0001 |
*
Significantly different than control (p<0.05).
#
Significantly different than mild OA (p<0.05).
BMI=body mass index; KL= Kellgren-Lawrence; WOMAC=Western Ontario and McMasters Universities Arthritis Index. Controls are defined as subjects having a KL score of 0, Mild OA are defined as subjects with a KL score of 1 or 2, and Severe OA are defined as subjects having a KL score of 3 or 4.