Table 5.
White matter structures/fiber pathways with significant correlations between FA/MD and duration of HIV infection
| WM Structures (JHU WM Atlas) |
FA (%)a,b | Associated WM Tractsb (JHU Tract Atlas) |
MD (%)a | Associated WM Tractsb (JHU Tract Atlas) |
|---|---|---|---|---|
| GCC | 32.4 | fp-mi, cin-cg-L, cin-cg-R | 45.5 | fp-mi, cin-cg-L, cin-cg-R |
| BCC | 27.3 |
fp-mi, cin-cg-L, slf-R, slf-L, slf-tp-R, atr-L |
37.6 |
fp-mi, cin-cg-L, atr-R, atr-L, slf-R, cin-cg-R, slf-L, slf-tp-R |
| SCC | 0.8 | cin-cg-L | 18.3 |
fp-ma, cin-cg-L, cin-hp-R, cin-cg-
R, cin-hp-L |
| ACR-R | 13.5 | fp-mi, cin-cg-R, slf-R, atr-R | 14.5 |
fp-mi, cin-cg-R, slf-R, unc-R, atr-R, ifof-R |
| ACR-L | 14.2 | cin-cg-L, fp-mi | 20.4 | fp-mi, ifof-L, atr-L, cin-cg-L, unc-L |
| SCR-R | 10.5 | cst-R, atr-R, slf-R | 8.5 | atr-R, cst-R |
| SCR-L | 10.1 | cst-L, ,slf-L, cing-cg-L | 7.3 | slf-L |
| PCR-R | 1.8 | Ifof-R, ilf-R | 8.9 |
Ifof-R, ilf-R, cin-cg-R, cin-hp-R, slf-R, fp-ma |
| PCR-L | 11.5 | cst-L, cin-cg-L, slf-L | 7.2 | cin-cg-L, ifof-L, slf-L |
| EC-L | NA | 4.0 | unc-L, ifof-L | |
| PTR-R | NA | 2.4 | Ifof-R | |
| PTR-L | NA | 1.9 | Ifof-L, ilf-L |
For each WM structures in the table, the extent of significant correlation was quantified by the percentage value between the number of skeleton voxels with significant correlation within each structure and the total number of skeleton voxels of each structure, with a mathematical definition similar to Eq.1. For each WM structure, WM fiber pathways listed in the table follow the descending order according to the percentage of significant correlation voxels that belong to a specific WM tract.
Abbreviations for fiber pathways (the same abbreviations are used for Table 5 as well as Fig. 3 and Fig. 4): Callosal fibers: fp-mi (forceps minor); fp-ma (forceps major); Association fibers: cin-cg (cingulum at the cingulate gyrus); cin-hp (cingulum at the hippocampus); slf (superior longitudinal fasciculus); slf-tp (superior longitudinal fasciculus at the temporal lobe); ifof (inferior fronto-occipital fasciculus); ilf (inferior longitudinal fasciculus); unc (uncinate fasciculus); Projection fibers: cst (corticospinal tract); atr (anterior thalamic radiation);
NA indicates there are no significant correlation between FA/MD value and the duration of HIV infection at a specific WM structure.