Skip to main content
. 2012 Dec 26;13:728. doi: 10.1186/1471-2164-13-728

Figure 2.

Figure 2

Hmt1-binding sites are enriched at ORF genes. A) Average Hmt1 enrichment profiles for all ORFs bound (“ALL ORFs), ORFs with high- (“≥ 15 mRNA/hr”), medium- (“1-15 mRNA/hr”), and low- (“ ≤ 1 mRNA/hr”) transcriptional frequencies. B) Histone enrichment/depletion calculations of promoters and genes for Hmt1-bound ORFs from ChromatinDB. C) Directed ChIP to assess the role of Hmt1 on the levels of pan-H4ac and H3K36me2. Representative ORFs bound-by Hmt1 were assayed for the level of the specified histone modification in WT and hmt1-null cells.