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. 2012 Dec 26;13:728. doi: 10.1186/1471-2164-13-728

Figure 3.

Figure 3

Hmt1-binding sites are enriched at tRNA genes. A) The average Hmt1-enrichment pattern across all Hmt1-bound tDNA features. B) Hmt1 loss-of-function mutants displayed increased tRNA abundance. Bar graph showing RNA hybridization analysis results on the relative abundance of mature tRNA tG(CCC) and tK(UUU) in the Hmt1-null (Δhmt1) and Hmt1-catalytically inactive mutants (G68R). Signals were normalized to the 5.8S rRNA (RNAPI transcript). C) Both pre- and mature tRNA abundance is increased in Hmt1 loss-of-function mutants. Bar graph showing RNA hybridization analysis results on the relative abundance of pre- and mature tRNA tL(UAG) in the Hmt1-null (Δhmt1) and Hmt1-catalytically inactive mutants (G68R). Signals were normalized to the 5.8S rRNA (RNAPI transcript).