Table 4.

Haplotype frequency in the study population in both affected and unaffected subjects

	P2X7, Gly150Arg	P2X4, Tyr315Cys	Population frequency	Affected frequency	Unaffected frequency	OR	95 % CI	p-Value	Number
H11a	G	A	97.4	95.5	98.2	0.44	(0.24–0.81)	0.008	867
H12b	A	A	1.3	2.1	0.88	2.08	(0.89–4.85)	0.090	22
H13c	G	G	0.8	1.4	0.56	2.44	(0.84–7.13)	0.103	15
H14d	A	G	0.5	0.88	0.31	2.60	(0.64–10.50)	0.18	9

Furthermore, the table shows the osteoporosis risk for each haplotype compared to all other haplotypes and their osteoporosis risk

OR odds ratio; CI confidence interval

^aWild-type

^bH12: Arg150-Tyr315

^cH13: Gly150-Cys315

^dH14: Arg150-Cys315