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. 2004 Mar;42(3):1185–1191. doi: 10.1128/JCM.42.3.1185-1191.2004

TABLE 3.

Distribution of the strain collection according to current NCCLS criteria for fluoroquinolone-susceptible H. influenzae and comparison with data on amino acid modifications in the QRDRs of GyrA and ParC

Quinolone NCCLS criteria (μg/ml)a Proposed zone diameter (mm)b No. (%) of strains with:
No mutation One mutation in GyrA QRDR Two mutations in either GyrA or ParC QRDR
Ciprofloxacin ≤1 ≥28 34 (81) 5 (12) 3 (7)
Levofloxacin ≤2 ≥18 33 (60) 7 (12.7) 15 (27.3)
Moxifloxacin ≤1 ≥23 33 (76.7) 5 (11.6) 5 (11.6)
a

The NCCLS criteria are presented in reference 23.

b

These proposed diameters were based on the distribution of the population in Fig. 2.