Table 1. Characteristics of the Study Population.
Median and interquartile ranges are presented unless otherwise specified
| No MAC (n=1541) | MAC (n=212) | p value | |
|---|---|---|---|
| Demographics | |||
| Age | 58 (53-65) | 66 (61-70) | <0.001 |
| Men (%) | 63.9 | 61.8 | 0.53 |
| Race (%) | <0.001 | ||
| Caucasian | 59.6 | 72.6 | |
| African American | 34.5 | 23.6 | |
| Other | 5.9 | 3.8 | |
| History | |||
| Hypertension (%) | 85.5 | 92 | 0.01 |
| Tobacco use (past or present, %) | 58.2 | 62.3 | 0.26 |
| Pack years | 13(4-30) | 14 (5-28) | 0.90 |
| Hyperlipidemia (%) | 80 | 86 | 0.04 |
| Diabetes duration, yrs (mean, SD) | 7.6 (6.6) | 9.8 (9.3) | <0.001 |
| Anthropomorphic | |||
| Waist circumference (in) | 41.5 (38.0-45.5) | 42 (38.5-46.0) | 0.13 |
| BMI | 32.1 (28.4-36.2) | 31.9 (28.6-36.4) | 0.99 |
| Labs | |||
| LDL-C (mg/dL) | 94 (77-116) | 94 (79-118) | 0.46 |
| Total Cholesterol (mg/dL) | 171 (148-196) | 170 (152-197) | 0.28 |
| HDL-C (mg/dL) | 45 (37-55) | 47 (41-56) | 0.01 |
| Triglycerides (mg/dL) | 115 (82-174) | 113 (84-161) | 0.46 |
| Serum Creatinine (mg/dl, mean, SD) | 0.9 (0.7-1.0) | 0.9 (0.7-1.0) | 0.46 |
| Hemoglobin A1c | 6.7 (6.1-7.7) | 6.7 (6.1-7.5) | 0.16 |
| C Reactive Protein (mg/L, mean SD) | 3.6 (5.3) | 3.7 (6.6) | 0.94 |
| Medications (%) | |||
| Statin | 57.2 | 62.8 | 0.12 |
| Fish oil | 14.1 | 16.5 | 0.35 |
| Fibrate | 6.8 | 5.7 | 0.55 |
| Metformin | 64.2 | 64.6 | 0.91 |
| Sulfonylurea | 34.5 | 40.1 | 0.14 |
| Thiazolidinedione | 22.9 | 25.5 | 0.41 |
| Insulin | 21.7 | 19.3 | 0.43 |
| Aspirin | 43.2 | 51.2 | 0.03 |
| Coronary Artery Calcium (%) | 61.4 | 90.4 | <0.001 |
| Coronary Artery Calcium Score | 22 (0-242) | 278 (42-746) | <0.001 |