. Author manuscript; available in PMC: 2013 Feb 10.

Published in final edited form as: Sci Transl Med. 2012 Mar 28;4(127):127ra37. doi: 10.1126/scitranslmed.3003689

Table 2.

Correlation of B7-H1 expression by melanocytes with the presence of immune cell infiltration.

Histology	Total	Number of cases/total cases (%)				P^*

		B7-H1⁺^†		B7-H1⁻

		TIL⁺^‡	TIL⁻	TIL⁺	TIL⁻
Benign nevi	40	14/14 (100)	0/14 (0)	4/26 (15)	22/26 (85)	<0.0001
Primary melanomas (in situ or invasive)	54	19/19 (100)	0/19 (0)	15/35 (43)	20/35 (57)	<0.0001
Metastases	56	23/24 (96)	1/24 (4)	7/32 (22)	25/32 (78)	<0.0001
All	150	56/57 (98)	1/57 (2)	26/93 (28)	67/93 (72)	<0.0001

Fisher’s exact test, two-sided, was conducted on the 2 × 2 matrix defined by B7-H1 (±) expression and TIL (±) for each lesion type.

^†

More than 5% melanocytes with membranous expression on IHC.

^‡

Including mild, moderate, and severe lymphocyte infiltrates and their associated histiocytes/macrophages.