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Comparison of Histologic Features Between Luschka Ducts and Invasive Gallbladder Adenocarcinoma
| Histologic Features |
Luschka Ducts | Invasive Gallbladder Adenocarcinoma |
|---|---|---|
| Location in gallbladder wall | Adventitia only | Full thickness |
| Architecture | Lobular, linear | Haphazard |
| Fibrosis | Concentric | Irregular |
| Cytology | Reactive atypia associated with inflammation | Nuclear variation (4:1) within a single gland |
| Mitoses | Minimal/none | Usually present |
| Other findings | Vascular and perineural invasion |
