TABLE 3.

Cox proportional hazards ratio estimates for the effect of covariates on recurrence-free survival in patients with surgically resected desmoids tumors

	Univariate		Multivariate
	HR (95 % CI)	P value	HR (95 % CI)	P value
Age at diagnosis (for each 5-year increase)	0.91 (0.82–0.99)	0.04	0.90 (0.82–0.98)	0.02
Race
White	Reference
Black	0.80 (0.47–1.36)	0.68	–	–
History of trauma in area of primary tumor	2.88 (1.20–6.90)	0.02	1.36 (0.57–3.24)	0.48
History of surgery in area of primary tumor	0.69 (0.37–1.30)	0.25	–	–
Desmoid during or shortly after pregnancy	0.73 (0.34–1.59)	0.43	–	–
Size >7 cm	0.73 (0.40–1.33)	0.30	–	–
Tumor location
Abdominal wall	Reference		Reference
Abdominal cavity	1.51 (0.41–5.63)	0.53	–
Extra-abdominal	4.66 (1.65–13.19)	0.01	3.28 (1.46–7.36)	0.01
Surgical margins
R0	Reference		Reference
R1	2.16 (1.17–4.01)	0.01	1.51 (0.85–2.66)	0.16
Receipt of systemic medical therapy	1.30 (0.46–3.66)	0.62	–	–
Receipt of radiotherapy	1.63 (0.86–3.86)	0.27	–	–