Table 2.
Patient, tumor, liver-directed surgery, and postoperative characteristics of the 52 patients who underwent surgical management of their liver metastasis
| Variable | No. of patients (%)(n = 52) |
|---|---|
| Patient characteristics | |
| Race, Caucasian | 47 (90) |
| Median age at surgery [range] (years) | 60 [40–85] |
| Hepatic metastasis | |
| Presentation, synchronous | 23 (46) |
| Number of lesions, multiple | 2 [1] |
| Size of largest liver lesion median [range] (cm) | 3 [1–10.5] |
| Distribution of liver lesions, bilobar | 13 (25) |
| Location of liver lesions | |
| Capsular/implant | 20 (38) |
| Deeply situated/parenchymal | 32 (62) |
| CA-125, >250 U/ml | 15 (29) |
| Concurrent extrahepatic disease | 44 (85) |
| Details of liver-directed surgery | |
| Surgical approach | |
| Open | 31 (60) |
| Laparoscopic | 21 (40) |
| Median number of tumors treated [range] | 2 [1–8] |
| Type of liver-directed therapy | |
| Resection only | 46 (88) |
| Radiofrequency ablation only | 2 (4) |
| Both | 4 (8) |
| Type of liver resection | |
| Nonanatomic wedge resection/single segment | 30 (58) |
| Bisegmentectomy | 14 (27) |
| Hemihepatectomy | 8 (15) |
| Extent of resection | |
| Minor (<3 segments) | 44 (85) |
| Major (≥ 3 segments) | 8 (15) |
| Concurrent lymphadenectomy | 29 (56) |
| Concurrent peritoneal debulking | 45 (87) |
| Median estimated blood loss [range] (ml) | 600 [50–2900] |
| Median units of blood transfusion [range] | 2 [0–7] |
| Margin | |
| R0 | 33 (63) |
| R1 | 8 (15) |
| R2 | 1 (2) |
| Unknown | 10 (19) |
| Postoperative course | |
| Median length of stay median (days) | 7 [3–24] |
| Grade of complications | |
| None | 24 (46) |
| I | 4 (8) |
| II | 5 (10) |
| III | 8 (15) |
| IV | 2 (4) |
| V | 0 |
| Unknown | 9 (17) |
| Perioperative treatment | |
| Preoperative chemotherapy | 14 (27) |
| Preoperative radiotherapy | 0 |
| Postoperative chemotherapy | 45 (87) |
| Postoperative radiotherapy | 2 (4) |