Fig 3.

Overview of sulfur metabolism in Y. lipolytica under high- versus low-sulfate conditions. (1) Serine-O-acetyltransferase. (2) Cysteine dioxygenase. The genes encoding these two enzymes are absent in S. cerevisiae. (3) Methionine salvage pathway. Genes highlighted in gray are repressed under high-methionine conditions. Genes in black boxes and highlighted in gray are overexpressed under high-methionine conditions. The reactions carried out by unidentified or assortments of enzymes are indicated with dotted arrows. Histograms are utilized only for compounds with significant differences. Values and error bars in histograms represent means with extreme values.