Table 2.
Proteins showing greater than three-fold changes with at least two unique peptides identified for each protein.
| Accession | Protein | SC (%)a | Fold Change b | Control dSpC c | Transgenic dSpC c |
|---|---|---|---|---|---|
| MUG1_MOUSE | Murinoglobulin-1 precursor | 14.7 | 4.2 | 15.5 | 3.7 |
| CO4B_MOUSE | Complement C4-B | 11.3 | 5.4 | 2.2 | 11.8 |
| PRDX6_MOUSE | Peroxiredoxin-6 | 57.6 | 4.6 | 1.4 | 6.4 |
| CNTN1_MOUSE | Contactin-1 | 6.5 | ↓ | 4.1 | 0 |
| CATB_MOUSE | Cathepsin B | 26.3 | 4.2 | 2.3 | 9.7 |
| CAH3_MOUSE | Carbonic anhydrase 3 | 39.6 | 7.6 | 1.1 | 8.4 |
| APOH_MOUSE | Beta-2-glycoprotein 1 | 12.8 | 4.4 | 4.4 | 1 |
| CSF1R_MOUSE | Macrophage colony-stimulating factor 1 receptor | 8.0 | 4.4 | 1.4 | 6.2 |
| PGK1_MOUSE | Phosphoglycerate kinase 1 | 35.5 | 3.6 | 1.7 | 6.1 |
| NDKB_MOUSE | Nucleoside diphosphate kinase B | 40.8 | 3.4 | 1.3 | 4.4 |
| FHL1_MOUSE | Four and a half LIM domains protein 1 | 24.3 | 3.9 | 1.3 | 5.1 |
| NELL2_MOUSE | Protein kinase C-binding protein NELL2 | 4.5 | −4.3 | 1.3 | 0.3 |
| MDHM_MOUSE | Malate dehydrogenase, mitochondrial | 38.5 | 4.1 | 1.2 | 4.9 |
| CSF1R_MOUSE | Macrophage colony-stimulating factor 1 receptor | 8.0 | 4.4 | 1.4 | 6.2 |
a
SC%: percentage of sequence coverage of the listed protein from sequenced tryptic peptides.
b
Fold Change: positive values are indicative of a fold change for transgenic CSF, negative values are fold changes for control CSF, and ↓ indicates the protein was only detected in control CSF.
c
dSpC: distributive spectral counts which represent the average spectral counts observed per run analysis on the mass spectrometer and corrected using distributive analysis for peptides shared by more than one protein.