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. Author manuscript; available in PMC: 2013 Feb 10.
Published in final edited form as: Methods Enzymol. 2010;481:195–230. doi: 10.1016/S0076-6879(10)81009-2

Table 9.1.

Properties of selected gold cluster labels

Gold cluster Bioconjugate reactive group(s) of cluster Labeled biomolecule moiety Nominal diameter
Undecagold Monoamino-, maleimido, Sulfo-NHS−, –SH, –NH2 0.8 nm
Nanogold Amino-, maleimido, Sulfo-NHS, –SH, –NH2 1.4 nm
Ni-NTA–Nanogold Ni(II) nitrilotriacetic acid (NTA) Polyhistidine, particularly His6 1.8, 5 nm
MPCs: Au25, Au38, Au68, Au102, Au144 Au –SH 0.9, 1.1, 1.3, 1.5, 2.0 nm