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Effect of plasmin on glial cell apoptosis. A172 cells were stimulated with plasmin (5 U/mL) for the length of time indicated and monitored flow cytometrically for apoptosis (programmed cell death) by staining with Annexin V. Representative flow cytometric histograms depict the effect of plasmin (open histogram) versus resting cells (filled histogram) on Annexin V expression. Serum starvation was used as a positive control for apoptosis.
