TABLE 1.
Drug susceptibility results for clinical strains of M. tuberculosis as determined by MB/BACT and BACTEC 460TB systemsa
| Drug (concnb) | No. of tests | No. S by both tests | No. of results that were:
|
No. R by both tests | Agreement (%) | |
|---|---|---|---|---|---|---|
| R with MB/BACT, S with 460TB | S with MB/BACT, R with 460TB | |||||
| INH (0.09) | 166 | 130 | 1 | 35 | 99.4 | |
| INH (0.4) | 94 | 66 | 28 | 100 | ||
| RIF (0.9) | 166 | 148 | 18 | 100 | ||
| EMB (3.5) | 166 | 151 | 3 | 12 | 98.2 | |
| EMB (7.0) | 82 | 76 | 4 | 2 | 95.1 | |
| STR (0.45) | 166 | 139 | 2 | 1 | 24 | 98.2 |
| STR (0.9) | 85 | 70 | 1 | 3 | 11 | 95.3 |
| PZA (200) | 166 | 154 | 3 | 9 | 98.2 | |
| Total | 1,091 | 934 | 3 | 15 | 139 | 98.3 |
a
INH, isoniazid; RIF, rifampin; EMB, ethambutol; STR, streptomycin; PZA, pyrazinamide; S, susceptible; R, resistant.
b
Concentrations are given in micrograms per milliliter.