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Functional outcomes on days 3, 5 and 7 post-injury using rotarod (A), grip strength (B), locomotor activity (C), and sticky tape removal (D) tests; and effect of P4 and VDH on infarct volume (E) and serum VDH level (F) following tMCAO. Values are expressed as means ± SEM. Significant difference #P<0.05 compared to sham; *P<0.05 compared to vehicle; and §P<0.05 compared to P4. Vaues in parentheses represent percent reduction in infarct volume.
