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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Diabetologia. 2012 Nov 24;56(3):598–607. doi: 10.1007/s00125-012-2782-z

Fig. 1.

Fig. 1

Obesity-induced ER stress leads to increased PTP1B protein levels. Representative western blots (a) and densitometric analysis (mean ± SEM, n=3) of PTP1B (b) and GRP78 (c) protein levels in gastrocnemius muscle of ob/ob and C57BL/6J lean mice receiving TUDCA or vehicle for 5 weeks. **p<0.01 compared with lean mice, ††p<0.01 compared with ob/ob mice. (d) Representative western blots of PTP1B, GRP78 and phospho- and total-eIF2α (p-eIF2α and p-eIF2α, respectively) protein levels in gastrocnemius muscle of C57BL/6J mice on a normal diet (ND) or high-fat diet (HFD)