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. 2004 Mar;42(3):1109–1114. doi: 10.1128/JCM.42.3.1109-1114.2004

TABLE 1.

Reproducibility testing for SIRE and PZA by the M960 system

Drug (μg/ml) Strainsa No. of tests performedb No. of results agreeing with ref- erence methodc Agreement (%)
INH (0.1) S 27 27 100
R 18 18 100
INH (0.4) S 27 27 100
R 18 17 94.4
RMB (1.0) S 27 27 100
R 18 18 100
EMB (5.0) S 27 26 94.4
R 18 18 100
EMB (7.5) S 27 27 100
R 18 18 100
SM (1.0) S 36 35 97.2
R 9 9 100
SM (4.0) S 36 36 100
R 9 9 100
    Total 315 312 99
PZA (100) S 36 36 100
R 9 8 88.9
    Total 45 44 97.8
a

S, susceptible; R, resistant.

b

With five strains of M. tuberculosis in triplicate from three separate inocula (thus, nine replicates per strain)

c

Agar proportion method for SIRE and B460 system for PZA.