Table 1.
Strain | Age, mo | N | Body Weight, g | EDL Weight, mg | EDL CSA, mm2 | Lo, mm |
---|---|---|---|---|---|---|
BL10 | 6 | 10 | 32.03 ± 0.57 | 13.90 ± 0.77 | 2.12 ± 0.12 | 14.09 ± 0.04 |
20 | 10 | 37.44 ± 0.64 | 13.00 ± 0.18 | 2.12 ± 0.03 | 13.14 ± 0.04 | |
mdx | 6 | 13 | 35.44 ± 0.42 | 16.73 ± 0.42† | 2.57 ± 0.07† | 13.93 ± 0.05 |
20 | 19 | 31.12 ± 0.56* | 15.95 ± 0.33† | 2.42 ± 0.05† | 14.13 ± 0.10† | |
ΔR2-15/ΔR18-23/ΔC | 6 | 10 | 34.89 ± 1.74 | 13.34 ± 0.38 | 2.01 ± 0.06 | 13.17 ± 0.03 |
20 | 9 | 41.92 ± 1.20a | 12.49 ± 0.61 | 2.01 ± 0.10 | 13.32 ± 0.06 | |
ΔR4-23/ΔC | 6 | 10 | 32.33 ± 0.48 | 12.51 ± 0.41 | 1.99 ± 0.06 | 13.46 ± 0.03 |
20 | 13 | 35.18 ± 1.24‡ | 12.12 ± 0.40 | 1.97 ± 0.06 | 13.19 ± 0.06 | |
ΔH2-R15 | 6 | 9 | 32.51 ± 0.79 | 12.77 ± 0.22 | 2.08 ± 0.03 | 13.19 ± 0.04 |
20 | 9 | 32.72 ± 1.40§ | 12.26 ± 0.28 | 1.94 ± 0.05 | 13.54 ± 0.09 |
Applicable values are means ± SE.
mdx mice are significantly different from age-matched BL10 mice.
mdx mice are significantly different from all other age-matched mouse strains.
ΔR4-23/ΔC mice are significantly different from age-matched mdx mice.
ΔH2-R15 mice are significantly different from age-matched BL10 mice.
ΔR2-15/ΔR18-23/ΔC mice are significantly different from all other age-matched mouse strains. EDL, extensor digitorum longus; CSA, cross-sectional area; Lo, optimal length.