TABLE 5.
Number of positive tests before and after start of ATC, with concordant and discordant results of ZN staining and MTD over the first 40 days of treatment
| Time of treatment | No. of patients/no. of specimens | No. of specimens positive bya:
|
No. of specimens that wereb:
|
|||||
|---|---|---|---|---|---|---|---|---|
| ZN staining | MTD | Culture | MTD+ and ZN− | MTD− and ZN+ | MTD+ and ZN+ | MTD+ and/or ZN+ | ||
| Pretreatment | 59/66 | 34/66 (52) | 25/66 (38) | 38/66 (58) | 11/66 (17) | 20/66 (30) | 14/66 (21) | 45/66 (68) |
| Days 2 to 5 | 34/34 | 8/34 (24) | 14/34 (41) | 12/34 (35) | 9/34 (26) | 3/34 (9) | 5/34 (15) | 17/34 (50) |
| Days 6 to 15 | 43/43 | 2/43 (5) | 12/43 (28) | 6/43 (14) | 12/43 (28) | 2/43 (5) | 0/43 | 14/43 (33) |
| Days 16 to 40 | 48/48 | 0/48 | 2/48 (4) | 0/48 | 2/48 (4) | 0/48 | 0/48 | 2/48 (4) |
| Days 41 to 80 | 35/35 | 0/35 | 0/35 | 1/35 (3) | ||||
| Days 260 to 280 | 36/36 | 0/36 | 0/36 | 0/36 | ||||
a
Each value is the number of positive specimens/total number of specimens. Values in parentheses are percentages. Where ZN staining and MTD results differed, the 95% confidence intervals were as follows (P values are in parentheses): for the pretreatment period, −4 to 31% (0.150); for days 2 to 5, −40 to 4% (0.146); and for days 6 to 15, −41 to −5% (0.013).
b
Each value is the specimens with the indicated results/total number of specimens. Values in parentheses are percentages. MTD+, MTD positive; MTD−, MTD negative; ZN−, ZN staining negative; and ZN+, ZN staining positive.