Table 1.
Focused Pi group heterocyclic library (53-61).
![]() |
|||
---|---|---|---|
| |||
Compound | SID |
![]() |
3CLpro IC50μM |
53 | 117686897 |
![]() |
10 |
54 | 117686898 |
![]() |
5.5 |
55 | 117686909 |
![]() |
Inactive |
56 | 117686901 |
![]() |
45 |
57 | 117686900 |
![]() |
Inactive |
58 | 117686899 |
![]() |
16% (100 μM) |
59 | 117686904 |
![]() |
Inactive |
60 | 117686905 |
![]() |
23% (100 μM) |
61 | 117686906 |
![]() |
23% (100 μM) |
IC50values are average of two independent runs using triplicate concentrations, ‘Inactive’ defined as %inhibition <15% at 100 μM, CV <0.3