TABLE 1. Summary of physiological variables during and after collagenase infusion*.
Group | Arterial Blood Gas |
BP (mm Hg) | HR (per min) | ||
---|---|---|---|---|---|
pH | PO2 (mm Hg) | PCO2 (mm Hg) | |||
during Tx | |||||
sham | 7.33 ± 0.03 | 186 ± 15 | 45 ± 3 | 81 ± 6 | 348 ± 40 |
needle | 7.39 ± 0.02 | 184 ± 21 | 43 ± 5 | 89 ± 6 | 369 ± 28 |
CI—15 U | 7.34 ± 0.05 | 192 ± 11 | 44 ± 8 | 89 ± 8 | 355 ± 33 |
CI—0.3 U | 7.32 ± 0.03 | 187 ± 5 | 46 ± 5 | 91 ± 5 | 362 ± 25 |
| |||||
30 mins after Tx | |||||
sham | 7.32 ± 0.01 | 185 ± 20 | 48 ± 5 | 84 ± 6 | 347 ± 48 |
needle | 7.38 ± 0.05 | 186 ± 14 | 44 ± 3 | 88 ± 8 | 359 ± 14 |
CI—0.15 U | 7.30 ± 0.08 | 188 ± 10 | 48 ± 9 | 88 ± 10 | 351 ± 33 |
CI—0.3 U | 7.29 ± 0.03 | 173 ± 17 | 50 ± 9 | 90 ± 5 | 380 ± 37 |
| |||||
24 hrs after Tx | |||||
sham | 7.50 ± 0.04 | 192 ± 12 | 36 ± 5 | 84 ± 5 | 348 ± 20 |
needle | 7.52 ± 0.02 | 181 ± 7 | 37 ± 7 | 78 ± 3 | 361 ± 17 |
CI—0.15 U | 7.47 ± 0.03 | 188 ± 11 | 38 ± 4 | 85 ± 9 | 359 ± 34 |
CI—0.3 U | 7.38 ± 0.06 | 179 ± 14 | 49 ± 9 | 90 ± 9 | 329 ± 46 |
| |||||
30 days after Tx | |||||
sham | 7.5 ± 0.06 | 182 ± 28 | 37 ± 8 | 94 ± 4 | 369 ± 9 |
needle | 7.47 ± 0.03 | 192 ± 12 | 36 ± 4 | 83 ± 5 | 364 ± 27 |
CI—0.15 U | 7.47 ± 0.03 | 190 ± 44 | 35 ± 4 | 87 ± 2 | 358 ± 39 |
There was no statistically significant difference between groups. Values are presented as the mean ± SD. Abbreviations: BP = blood pressure; CI = collagen infusion; HR = heart rate; Tx = treatment.