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. Author manuscript; available in PMC: 2013 Feb 11.
Published in final edited form as: J Neurosurg. 2012 Nov 30;118(2):465–477. doi: 10.3171/2012.10.JNS111836

TABLE 1. Summary of physiological variables during and after collagenase infusion*.

Group Arterial Blood Gas
BP (mm Hg) HR (per min)
pH PO2 (mm Hg) PCO2 (mm Hg)
during Tx
sham 7.33 ± 0.03 186 ± 15 45 ± 3 81 ± 6 348 ± 40
needle 7.39 ± 0.02 184 ± 21 43 ± 5 89 ± 6 369 ± 28
CI—15 U 7.34 ± 0.05 192 ± 11 44 ± 8 89 ± 8 355 ± 33
CI—0.3 U 7.32 ± 0.03 187 ± 5 46 ± 5 91 ± 5 362 ± 25

30 mins after Tx
sham 7.32 ± 0.01 185 ± 20 48 ± 5 84 ± 6 347 ± 48
needle 7.38 ± 0.05 186 ± 14 44 ± 3 88 ± 8 359 ± 14
CI—0.15 U 7.30 ± 0.08 188 ± 10 48 ± 9 88 ± 10 351 ± 33
CI—0.3 U 7.29 ± 0.03 173 ± 17 50 ± 9 90 ± 5 380 ± 37

24 hrs after Tx
sham 7.50 ± 0.04 192 ± 12 36 ± 5 84 ± 5 348 ± 20
needle 7.52 ± 0.02 181 ± 7 37 ± 7 78 ± 3 361 ± 17
CI—0.15 U 7.47 ± 0.03 188 ± 11 38 ± 4 85 ± 9 359 ± 34
CI—0.3 U 7.38 ± 0.06 179 ± 14 49 ± 9 90 ± 9 329 ± 46

30 days after Tx
sham 7.5 ± 0.06 182 ± 28 37 ± 8 94 ± 4 369 ± 9
needle 7.47 ± 0.03 192 ± 12 36 ± 4 83 ± 5 364 ± 27
CI—0.15 U 7.47 ± 0.03 190 ± 44 35 ± 4 87 ± 2 358 ± 39
*

There was no statistically significant difference between groups. Values are presented as the mean ± SD. Abbreviations: BP = blood pressure; CI = collagen infusion; HR = heart rate; Tx = treatment.