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. 2012 Dec 5;109(4):1078–1090. doi: 10.1152/jn.00124.2012

Fig. 3.

Fig. 3.

Modulatory effect of elevated temperature on the Bz-insensitive NaCl CT response in the absence and presence of NGCC. A: rat tongue was first stimulated with R and then with N+Bz solutions containing 0 (control) or 2 μM NGCC maintained at 23°C, 33°C, 36.8°C, 39°C, 41.7°C, 50°C, and 55°C with the stimulus series 3 protocol. The normalized CT response data at the various temperatures shown were fitted to Eq. 4. Tonic responses to increasing temperature were compared in the absence and presence of 2 μM NGCC. Significant differences were found for increasing temperature (P = 0.01 for both, 2-way ANOVA; Bonferroni corrected) and their interactions (P = 0.001). B: mean normalized CT response in 3 rats to N+Bz and N+Bz+2 μM NGCC at 22.5°C and 42.5°C. *P = 0.0001 with respect to CT response to N+Bz at 22.5°C (unpaired).