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. 2013 Feb 11;8(2):e56347. doi: 10.1371/journal.pone.0056347

Figure 4. Gender influences susceptibility to infection in F1 offspring of A/J females crossed with C57BL/6 males.

Figure 4

Age-matched males and females of parental A/J and C57BL/6 mouse strains together with heterozygous F1 offspring (F1(AXB)) of A/J females crossed with C57BL/6 males were infected i.p. with 1000 trypomastigotes of the Y strain of T. cruzi. Mouse numbers were as follows: A/J male (n = 11), A/J female (n = 8), C57BL/6 male (n = 11) C57BL/6 female (n = 8), F1(AXB) male (n = 9), F1(AXB) female (n = 11). Mortality was evaluated by daily inspection of the cages. Data are representative of those found in seven independent experiments. (*) indicates P<0.05 in comparisons between F1(AXB) males and the other experimental groups.