Table 6. Selection of NMSS items by stepwise logistic regression1 to discriminate between PD patients (n = 200) and HFS patients (n = 75).
Selected NMSS items in the order selected | Chi-Square Score | p-value | Cumulative area under the ROC curve | Odds Ratio | 95% Wald Confidence Intervals | Wald p-value |
Presence of ‘constipation’ | 37.2 | < 0.0001 | 0.672 | 37.0 | [6.80, 200] | < 0.0001 |
NMSS score for ‘restless legs’ | 10.8 | 0.001 | 0.726 | 2.10 | [1.41, 3.13] | 0.001 |
NMSS score for ‘altered interest in sex’ | 10.6 | 0.001 | 0.789 | 1.68 | [1.15, 2.46] | 0.007 |
Presence of ‘difficulty falling or staying asleep’ | 8.5 | 0.004 | 0.811 | 0.15 | [0.06, 0.36] | <0.0001 |
Presence of ‘weight change’ | 9.8 | 0.002 | 0.829 | 17.5 | [2.45, 125] | 0.004 |
NMSS score for ‘pain’ | 7.9 | 0.005 | 0.850 | 1.24 | [1.09, 1.43] | 0.002 |
Presence of ‘forget to do things’ | 6.4 | 0.011 | 0.864 | 0.39 | [0.19, 0.80] | 0.011 |
NMSS score for ‘dribbling saliva’ | 6.3 | 0.012 | 0.877 | 2.06 | [1.24, 3.42] | 0.005 |
Presence of ‘altered sense of taste or smell’ | 5.7 | 0.017 | 0.887 | 9.09 | [1.77, 45.5] | 0.008 |
NMSS score for ‘difficulty experiencing pleasure’ | 4.8 | 0.029 | 0.894 | 1.26 | [1.05, 1.52] | 0.012 |
Presence of ‘feel nervous’ | 5.2 | 0.023 | 0.8972 | 0.35 | [0.14, 0.88] | 0.025 |
Significance level to enter = level to stay = 0.05.
Final model AUC = 0.897.