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. 2013 Feb 11;8(2):e55490. doi: 10.1371/journal.pone.0055490

Figure 1. Estimating the frequency of highly-susceptible TMEM154 alleles in global sheep populations.

Figure 1

The “c” allele of SNP OAR17_5388531 is in linkage disequilibrium with the “g” nucleotide allele in codon 35 (gaa) of TMEM154. Genotypes for OAR17_5388531 were derived from the ISGC ovine SNP50k data set [11]. Numbers in parentheses for each breed group indicate the number of animals genotyped. The 11 breed groups with asterisks were genotyped for TMEM154 E35 by Sanger sequencing [9] and were included for comparison with the 74 ISGC breed groups.