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Percent cell viability of mecamylamine + nicotine pre-treatment in N2a, N2a-APP695 and N2a-APPSweΔ9PS1 cells. Mecamylamine (uM) was added 2 hrs before nicotine (0.01 uM) treatment. MTT Assay was performed 72h following nicotine pre-treatment. Values are mean ± SEM, n=5. * P<0.05 **P<0.01, ***P<0.001 compared to nicotine 0.01uM.
