Table 1.
Clinical and Laboratory Data in Patients with SLE and Controls
| Parameter | Patients (N = 50) |
Controls (N = 22) |
P Value |
|---|---|---|---|
| Age (years) | 38 ± 12 | 34 ± 12 | 0.15 |
| Female gender (%) | 92 | 82 | 0.19 |
| Non hispanic whites and Hispanic (%) | 28 and 60 | 36 and 50 | 0.71 |
| Body mass index (kg/m2) | 27 ± 5 | 27 ± 6 | 0.75 |
| *Systolic blood pressure (mmHg) | 124 ± 14 | 116 ± 8 | 0.01 |
| *Diastolic blood pressure (mmHg) | 77 ± 10 | 73 ± 7 | 0.03 |
| *Mean arterial blood pressure (mmHg) | 93 ± 10 | 87 ± 6 | 0.01 |
| Ambulatory hypertension (%) | 14 | 0 | 0.09 |
| Hypertension or on vasodilator therapy (%) | 28 | 0 | 0.004 |
| Smoking | 54 | 23 | 0.02 |
| Cholesterol (mg/dl) | 182 ± 45 | 185 ± 45 | 0.82 |
| Triglycerides (mg/dl) | 153 ± 77 | 160 ± 104 | 0.79 |
| Dyslipidemia | 63 | 38 | 0.07 |
| Diabetes mellitus (%) | 12 | 0 | 0.17 |
| Any atherogenic risk factor (%) | 72 | 36 | 0.01 |
| Post-menopausal status (%) | 15 | 11 | 1.0 |
| Hematocrit (%) | 39 ± 4 | 41 ± 4 | 0.02 |
| Platelets (k/mm3) | 240 ± 91 | 274 ± 44 | 0.04 |
| White blood cell count (k/mm3) | 5.8 ± 2.3 | 6.5 ± 1.7 | 0.19 |
| Creatinine (mg/dl) | 0.83 ± 0.32 | 0.72 ± 0.10 | 0.04 |
| Albumin (g/dL) | 3.9 ± 0.6 | 4.2 ± 0.4 | 0.01 |
| P-selectin (ng/mL) | 41 ± 21 | 39 ± 16 | 0.62 |
| C3a (pg/mL) | 2246 ± 3255 | 2096 ± 2217 | 0.83 |
| C5a (pg/mL) | 31 ± 11 | 29 ± 10 | 0.54 |
| Quantitative D-dimer (ug/ml) | 1.0 ± 3.0 | 0.3 ± 0.4 | 0.15 |
| Platelet derived microparticles (uL) | 553 ± 668 | 517 ± 592 | 0.83 |
| Monocyte derived microparticles (uL) | 442 ± 668 | 477 ± 487 | 0.81 |
| Endothelium derived microparticles (uL) | 162 ± 235 | 154 ± 122 | 0.87 |
Data presented as mean ± SD or %.
*
Ambulatory blood pressure.