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. 2013 Feb 4;171(3):338–345. doi: 10.1111/cei.12023

Figure 2.

Figure 2

Administration of azithromycin attenuates development of acute graft-versus-host disease (GVHD) histopathological features. Skin, small intestine and liver samples were obtained on day 7 post-bone marrow transplantation (BMT) for pathological analysis (n = 3 per group). Paraffin sections were stained with haematoxylin and eosin (original magnification: skin, ×600; small intestine, ×100 liver; ×200). (a–i) Histology of the skin (a–c), small intestine (d–f) and liver (g–i) from BALB/c→BALB/c recipients (a,d,g), B6→BALB/c recipients (b,e,h), and B6→AZM-treated BALB/c recipients (c,f,i). Black arrowheads: inflammatory response associated with acute GVHD. (j,k) Pathology scores of small intestine and liver from the same recipients. Coded slides were scored semiquantitatively as described in Materials and methods. All data are expressed as the mean ± standard deviation (n = 3 per group). **P < 0·001.