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. 2013 Jan 22;5(2):173–176. doi: 10.1002/emmm.201202387

Figure 1. The discovery of channelrhodopsins.

Figure 1

  1. Phototaxis of the Chlamydomonas wild type strain CW2 and the channelrhodopsin-defective mutant H17.
  2. Electrophysiological recording from oocytes (in the centre, with two electrodes, left and right) allows investigation of light-induced (via light guide, below oocyte) currents, e.g. mediated by rhodopsins.
  3. Light-induced currents mediated by channelrhodopsin-2 (two illuminations for 1 s, blue bars) at −100 mV.
  4. Model of channelrhodopsin opening, following light absorption and isomerization of covalently bound retinal.