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Self renewal – summary of WT formation in NOD-SCID and NOG mice by sorted NCAM+ALDH+ p-WT Xn derived cells
| Number of cells injected | Type of cells injected | Tumours/injection | p-values | ||
|---|---|---|---|---|---|
| NOD-SCID mice | NOG mice | ||||
| W011 p-WT Xn | W013 p-WT Xn | W011 p-WT Xn | |||
| 200 | NCAM+ALDH1+ | 2/4 | 1/4 | 3/4 | <200 cells |
| NCAM+ALDH1− | 0/4 | 0/4 | 0/4 | 0.007 | |
| 500 | NCAM+ALDH1+ | 3/4 | 1/4 | 2/4 | <500 cells |
| NCAM+ALDH1− | 0/4 | 0/4 | 0/4 | 0.0002 | |
| 1 × 103 | NCAM+ALDH1+ | 3/4 | 3/4 | 3/4 | <1000 cells |
| NCAM+ALDH1− | 0/4 | 0/4 | 0/4 | ||
| Non-sorted | 2/4 | 2/4 | – | 0.0001 | |
