Table 3.
Crude and adjusted odds ratios of current asthma per concentration quartile and per log10 IQR increase in MEP, MnBP, MiBP, MBzP, MCPP, MCOP, and MCNP.
| Phthalate metabolite | Concentration (µg/L) | Noncases (n) | Cases (n) | Crude OR (95% CI) | aORa (95% CI) |
|---|---|---|---|---|---|
| MEP in quartiles | ≤ 32.6 (ref) | 119 | 36 | 1 | 1 |
| > 32.6–56.7 | 125 | 31 | 0.82 (0.47, 1.4) | 0.97 (0.55, 1.7) | |
| > 56.7–94.4 | 127 | 29 | 0.76 (0.43, 1.4) | 0.85 (0.47, 1.6) | |
| > 94.4 | 123 | 32 | 0.61 (0.50, 1.5) | 0.99 (0.55, 1.8) | |
| MEP per log10 IQR | 494 | 128 | 0.82 (0.33, 2.1) | 0.98 (0.39, 2.5) | |
| MnBP in quartiles | ≤ 93.6 (ref) | 123 | 33 | 1 | 1 |
| > 93.6–138 | 124 | 34 | 1.0 (0.60, 1.8) | 1.2 (0.65, 2.0) | |
| > 138–209 | 123 | 32 | 0.99 (0.56, 1.8) | 1.1 (0.62, 2.0) | |
| > 209 | 124 | 29 | 0.90 (0.49, 1.6) | 0.96 (0.51, 1.8) | |
| MnBP per log10 IQR | 494 | 128 | 0.83 (0.63, 1.1) | 0.85 (0.64, 1.1) | |
| MiBP in quartiles | ≤ 31.4 (ref) | 130 | 28 | 1 | 1 |
| > 31.4–49.2 | 121 | 33 | 1.3 (0.75, 2.4) | 1.3 (0.74, 2.4) | |
| > 49.2–88.4 | 123 | 32 | 1.3 (0.72, 2.4) | 1.4 (0.73, 2.5) | |
| > 88.4 | 120 | 35 | 1.5 (0.82, 2.7) | 1.5 (0.80, 2.7) | |
| MiBP per log10 IQR | 494 | 128 | 1.1 (0.88, 1.5) | 1.1 (0.87, 1.5) | |
| MBzP In quartiles | ≤ 16.9 (ref) | 121 | 34 | 1 | 1 |
| > 16.9–29.2 | 130 | 25 | 0.70 (0.39, 1.3) | 0.70 (0.39, 1.3) | |
| > 29.2–52.9 | 128 | 27 | 0.79 (0.44, 1.4) | 0.83 (0.45, 1.5) | |
| > 52.9 | 115 | 42 | 1.4 (0.81, 2.4) | 1.3 (0.75, 2.4) | |
| MBzP per log10 IQR | 494 | 128 | 1.2 (0.91, 1.5) | 1.2 (0.88, 1.5) | |
| MCPP in quartiles | ≤ 4.6 (ref) | 121 | 36 | 1 | 1 |
| > 4.6–7.5 | 132 | 23 | 0.61 (0.34, 1.1) | 0.60 (0.33, 1.1) | |
| > 7.5–12.8 | 124 | 33 | 0.95 (0.54, 1.7) | 1.0 (0.57, 1.9) | |
| > 12.8 | 117 | 36 | 1.1 (0.62, 2.1) | 1.2 (0.63, 2.1) | |
| MCPP per log10 IQR | 494 | 128 | 0.99 (0.75, 1.3) | 0.99 (0.74, 1.3) | |
| MCOP in quartiles | ≤ 3.5 (ref) | 127 | 30 | 1 | 1 |
| > 3.5–6.0 | 131 | 27 | 0.93 (0.52, 1.7) | 1.0 (0.60, 1.9) | |
| > 6.0–10.2 | 123 | 31 | 1.2 (0.65, 2.1) | 1.2 (0.67, 2.3) | |
| > 10.2 | 113 | 40 | 1.7 (0.94, 3.0) | 1.9 (1.0, 3.3) | |
| MCOP per log10 IQR | 494 | 128 | 1.3 (0.96, 1.6) | 1.3 (0.98, 1.7) | |
| MCNP in quartiles | ≤ 1.4 (ref) | 145 | 29 | 1 | 1 |
| > 1.4–2.1 | 113 | 26 | 1.2 (0.7, 2.2) | 1.2 (0.63, 2.2) | |
| > 2.1–3.5 | 123 | 31 | 1.4 (0.8, 2.5) | 1.5 (0.84, 2.8) | |
| > 3.5 | 113 | 42 | 2.2 (1.2, 3.9) | 2.2 (1.2, 4.0) | |
| MCNP per log10 IQR | 494 | 128 | 1.3 (1.0, 1.6) | 1.3 (1.0, 1.7) | |
| Abbreviations: IQR, interquartile range; ref, reference. aAdjusted for urine SG, sex, parental asthma, and household income. | |||||