Table 1.
Biomarker | All (N = 354, n = 30) | Men (N = 180, n = 15) | Women (N = 174,a n = 15) | p-Value sex differenceb | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Mean | Range | Mean | Range | Mean | Range | |||||
Cd | ||||||||||
U-Cd (µg/L) | 0.12 | < LODc–1.1 | 0.11 | < LODc–0.53 | 0.14 | < LODc–1.1 | 0.77 | |||
U-CdCrea (µg/gC)d | 0.11 | 0.01–0.52 | 0.08 | 0.01–0.25 | 0.16 | 0.02–0.52 | 0.06 | |||
U-CdSG (µg/L)e | 0.12 | 0.01–0.71 | 0.09 | 0.01–0.31 | 0.14 | 0.02–0.71 | 0.12 | |||
U-Cd/hr (µg/hr)f | 0.007 | 0.0007–0.03 | 0.007 | 0.0009–0.02 | 0.008 | 0.0007–0.03 | 0.54 | |||
Alb | ||||||||||
U-Alb (mg/L) | 7.5 | < LODc–121 | 10.5 | < LODc–121 | 4.4 | < LODc–33 | 0.44 | |||
U-AlbCrea (mg/gC)d | 6.3 | 1.1–78 | 7.4 | 1.2–42 | 5.3 | 1.1–78 | 0.37 | |||
U-AlbSG (mg/L)e | 6.3 | 0.28–65 | 7.9 | 0.32–65 | 4.7 | 0.28–62 | 1.0 | |||
U-Alb/hr (mg/hr)f | 0.47 | 0.02–4.9 | 0.64 | 0.08–4.5 | 0.31 | 0.02–4.9 | 0.26 | |||
A1M | ||||||||||
U-A1M (mg/L) | 2.4 | < LODc–47 | 3.1 | 0.12–47 | 1.7 | < LODc–10 | 0.12 | |||
U-A1MCrea (mg/gC)d | 2.0 | 0.11–31 | 2.2 | 0.11–31 | 1.7 | 0.22–7.6 | 0.35 | |||
U-A1MSG (mg/L)e | 1.9 | 0.13–32 | 2.3 | 0.13–32 | 1.5 | 0.13–5.8 | 0.07 | |||
U-A1M/hr (mg/hr)f | 0.14 | 0.002–1.8 | 0.18 | 0.01–1.8 | 0.10 | 0.002–0.54 | 0.02 | |||
Urinary flow rate (mL/hr) | 89.2 | 8.0–420 | 84.9 | 8.0–336 | 93.6 | 11–420 | 0.65 | |||
Mean values are calculated as mean of 30 individual means; ranges include all 354 urine samples. aOne woman provided samples over 1 day only (6 samples).bTests of sex difference were performed on 30 individual means (Wilcoxon rank-sum test). cValues < LOD were replaced with LOD/√_2 in calculation. dConcentrations adjusted for U-Crea concentration (mean U-Crea, 1.2 g/L). eConcentrations adjusted for SG (mean SG, 1.017). fExcretion rates. |