Table 3.

Mean regression coefficients for the association of U-Cd (dependent variable) with urinary flow (mL/hr) and U-Alb (Model 1) or urinary flow and U-A1M (Model 2), based on separate within-individual models for 30 participants.

Adjustment methoda	Model 1			Model 2
	β1 (p-value)b	β2 × 10–3 (p-value)b	Intercept	β1 (p-value)b	β2 × 10–3 (p-value)b	Intercept
Excretion rate	0.013 (< 0.001)	0.016 (0.004)	0.0035	0.025 (< 0.001)	0.011 (0.007)	0.0042
SG adjusted	0.014 (< 0.001)	–0.45 (0.02)	0.093	0.019 (< 0.001)	–0.56 (0.02)	0.11
U-Crea adjusted	0.007 (0.007)	–0.096 (0.90)	0.098	0.014 (< 0.001)	–0.089 (0.99)	0.094
Individual regressions based on data for 6 samples per day over 2 days (354 total samples; one participant had 6 samples only). For each individual participant, Model 1: U-Cd = β1(urinary flow rate) + β2 (U-Alb) + intercept; Model 2: U-Cd = β1(urinary flow rate) + β2 (U-A1M) + intercept. aExcretion rate in µg/hr for U-Cd, mg/hr for U-Alb and U-A1M; SG-adjusted concentrations in µg/L for Cd, mg/L for albumin and A1M; U-Crea–adjusted concentrations in µg/g creatinine for Cd, mg/g creatinine for U-Alb and U-A1M. bp-Value for significant deviation of the mean regression coefficient across individuals based on Wilcoxon signed rank test.