Table 3.
Adjusted linear models for measures of cognition at 5 and 7 years of age (standard score), per 10-fold increase in maternal prenatal and child ∑PBDE concentration (ng/g, lipid-adjusted).
| Outcome | Maternal ∑PBDEa,b | Child ∑PBDEb,c | |||
|---|---|---|---|---|---|
| n | β (95% CI) | n | β (95% CI) | ||
| Assessment of 5-year-olds | |||||
| PPVT | 252 | 0.4 (–5.1, 5.9) | |||
| Performance IQ | 256 | 0.9 (–3.5, 5.3) | |||
| Assessment of 7-year-olds | |||||
| Full-Scale IQ | 231 | –4.7 (–9.4, 0.1)* | 248 | –5.6 (–10.8, –0.3)** | |
| Verbal Comprehension IQ | 258 | –5.5 (–10.0, –1.0)**,# | 269 | –4.3 (–9.4, 0.8)* | |
| Perceptual Reasoning IQ | 258 | –2.4 (–7.6, 2.9) | 269 | –5.2 (–11.1, 0.7)* | |
| Working Memory IQ | 231 | –2.4 (–7.2, 2.3)# | 249 | –2.3 (–7.4, 2.8) | |
| Processing Speed IQ | 232 | –2.3 (–6.8, 2.3) | 249 | –6.6 (–11.4, –1.8)** | |
| aMaternal PBDE models control for child’s age, sex, home score at 6-month visit, language of assessment, and maternal years living in United States before giving birth. bSum of four PBDE congeners: BDEs 47, 99, 100, and 153. cChild PBDE models control for child’s age, sex, home score at 7-year visit, maternal PPVT, language of examination, maternal years living in the United States before giving birth, parity, and prenatal exposure to environmental tobacco smoke. *p < 0.1. **p ≤ 0.05. #Digression from linearity at p < 0.10. | |||||