Skip to main content
. Author manuscript; available in PMC: 2013 Feb 12.
Published in final edited form as: Hepatology. 2009 Jun;49(6):1972–1981. doi: 10.1002/hep.22891

Table 2.

Effect of nor-Bile Acids on Fluid Secretion in IBDUs using HCO3 - Containing and HCO3-Free Buffer

Variable % Increase in
Luminal Area after
30 Minutes
n P value
HCO3 buffer
  Control 12 ± 5 9
  UDCA 250 µM 42 ± 13 9 <0.001*
  norUDCA 250 µM 65 ± 21 33 <0.001*
<0.01
  T-norUDCA 250 µM 49 ± 18 18 <0.001*
<0.05
NS
  dinorUDCA 250 µM 29 ± 12 18 <0.01*
<0.001
<0.05
HCO3-free HEPES buffer
  Control 15 ± 5 8
  norUDCA 250 µM 31 ± 11 10 <0.01*
  T-norUDCA 250 µM 33 ± 7 8 <0.01*
NS
  dinorUDCA 250 µM 21 ± 12 8 NS*
NS

Values are expressed as the mean ± standard deviation.

Abbreviations: HEPES, 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid; NS, not significant.

*

P < 0.05 versus control.

P < 0.05 versus norUDCA 250 µM.

P < 0.05 versus UDCA 250 µM.

HHS Vulnerability Disclosure