Table 5.
Effects of nor-Bile Acids on Liver Enzymes in Mdr2−/− Mice
Variable | Control (n = 10) |
norUDCA (n = 8) |
T-norUDCA (n = 9) |
dinorUDCA (n = 7) |
---|---|---|---|---|
ALT (U/L) | 395 ± 101 | 272 ± 35* | 331 ± 100 | 903 ± 177*,† |
AP (U/L) | 212 ± 33 | 170 ± 22* | 188 ± 34 | 940 ± 175*,† |
Control, standard chow-fed animals; norUDCA, norUDCA–fed animals; T-norUDCA, tauro-norUDCA–fed animals; dinorUDCA, dinorUDCA–fed animals. Values are expressed as the mean ± standard deviation.
P < 0.05 versus control.
P < 0.05 versus norUDCA.