Table 2. Kinetic rates and binding affinity of 80R antibody and ACE2 to S1-lg.
Kon, M-1·s-1 | Koff, s-1 | Ka, M-1 | Kd, M | |
---|---|---|---|---|
80R scFv | 2.29 × 105 | 8.36 × 10-3 | 3.10 × 107 | 3.23 × 10-8 |
80R IgG1 | 3.88 × 105 | 6.18 × 10-4 | 6.28 × 108 | 1.59 × 10-9 |
ACE2 | 2.47 × 105 | 4.20 × 10-4 | 5.88 × 108 | 1.70 × 10-9 |
Kinetic rates and Ka and Kd were calculated using bia-evaluation software.