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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Future Oncol. 2012 Nov;8(11):1407–1425. doi: 10.2217/fon.12.138

Figure 2. Role of miRNAs in the development and progression of oral squamous cell carcinoma.

Figure 2

Two important epigenetic mechanisms support OSCC tumorigenesis: overexpression of oncogenic miRNAs (or oncoMiRs) and underexpression of tumor suppressor miRNAs (or tsMiRs). Listed in this figure are some of the most important miRNAs and their gene targets that have emerged as key regulators of gene expression in oral cancer.

OSCC: Oral squamous cell carcinoma.