Table 1.
Characteristics of included subjects.
| CD (n = 40) | UC (n = 42) | HC (40) | |
|---|---|---|---|
| Gender (female/male) | 21/19 | 20/22 | 20/20 |
| Age (years) | 33.58 (28.87–38.28) | 41.64 (37.18–46.10) | 35.48 (30.06–40.89) |
| BMI (kg/m2) | 19.29 (18.81–19.76)*** | 20.00 (19.41–20.59)*** | 22.84 (22.10–23.58) |
| Smoking (yes/no) | 8/32 | 22/20** | 3/37 |
| Extent | |||
| Ileitis | 3 | ||
| Ileocolitis | 15 | ||
| Colitis | 22 | ||
| Proctosigmoiditis | 13 | ||
| Left-sided colitis | 20 | ||
| Pancolitis | 9 | ||
| Therapy | |||
| 5-ASA/SASP | 36 | 42 | |
| Glucosteroids | 22 | 16 | |
| AZA | 8 | 6 | |
| Infliximab | 6 | 1 | |
| Surgery | 1 | 1 | |
| Endoscopic score† | 3.200 (1.650–6.000) | 2.000 (1.000–3.000) |
CD: Crohn's disease; UC: ulcerative colitis; HC: healthy controls; BMI: body mass index; 5-ASA: 5-aminosalicylic acid; SASP: sulfasalazine; AZA: azathioprine; ***P < 0.0001, significance is the difference from healthy controls; **P < 0.01, significance is the difference from patients with Crohn's disease; †values are medians and 25%–75% percentile, simplified endoscopic score in Crohn's disease (SES-CD) is used to validate endoscopic severity in Crohn's disease, and Baron score is used to validate endoscopic severity in ulcerative colitis, respectively.