Table 3.
Univariate and multivariate logistic regression analysis of risk factors for in-hospital mortality among severe falciparum malaria patients with acute kidney injury.
| Parameters | Univariate analysis | Multivariate analysis* | ||
|---|---|---|---|---|
| OR† (95% CI‡) | P value | OR† (95% CI‡) | P value | |
| Glasgow coma scale ≤10 | 8.477 (3.852–18.654) | <0.001 | ||
| Number of WHO criteria ≥4 | 22.500 (7.625–66.396) | <0.001 | ||
| Inotropic drug | ||||
| No | 1.000 | 1.000 | ||
| Dopamine | 17.185 (5.945–49.679) | <0.001 | 7.172 (1.827–28.145) | 0.005 |
| Adrenaline | 130.500 (34.422–494.744) | <0.001 | 14.502 (2.874–73.166) | 0.001 |
| Mechanical ventilator | 37.266 (12.450–111.546) | <0.001 | 10.806 (2.569–45.459) | 0.001 |
| WBC# >12.0 × 109/L | 5.286 (2.602–10.736) | <0.001 | 3.982 (1.146–13.836) | 0.030 |
| Potassium >5.5 mmol/L | 10.427 (2.731–39.808) | 0.001 | ||
| Bicarbonate <15 mmol/L | 6.195 (2.509–15.295) | <0.001 | ||
| Blood sugar <60 mg/dL | 12.000 (1.379–104.410) | 0.024 | ||
| AST€ >500 U/L | 7.429 (2.646–20.858) | <0.001 | ||
| ALT|| >500 U/L | 13.875 (1.497–128.561) | 0.021 | ||
| Albumin ≤2.5 mg/dL | 2.597 (1.205–5.597) | 0.015 | ||
*Unaffected factors including the Glasgow coma scale, total WHO criteria, potassium, bicarbonate, blood sugar, ALT||, and albumin.†OR: odds ratio. ‡CI: confidence intervals. #WBC: white blood cell count. €AST: aspartate aminotransferase. ||ALT: alanine aminotransferase.