FIG. 1.

General overview of the process of long non-coding RNA (lncRNA) detection and analysis for clinical application. Samples are collected from patients, from either tumor tissue or body fluids. For lncRNA detection, extracted RNA is analyzed by microarray, next-generation RNA sequencing, or real time PCR, and computational analyses determine differentially expressed lncRNAs. Selected lncRNA candidates are subjected to functional studies that can lead to the development of new drugs or other clinical applications.