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. 2013 Jan;168(1):11–18. doi: 10.1111/j.1476-5381.2012.01996.x

Figure 1.

Figure 1

Chemical structure of EO9 (A) and scheme for possible activation of EO9 leading to DNA damage (B). 2e and 1e in panel B represent two-electron reduction (via enzymes such as NQO1) and one-electron reduction (via enzymes such as cytochrome P450 reductase) respectively. Q, SQ and HQ denote quinone (parent compound), semi-quinone (one-electron reduction product) and hydroquinone (two-electron reduction product) respectively.