Table 2.
In vivo selectivity of antidepressant drugs in mice measured by intracerebral microdialysis
| Ratio of AUC values in WT mice | Escitalopram (8 mg·kg−1, i.p.) | Citalopram (8 mg·kg−1, i.p.) | Paroxetine (8 mg·kg−1, i.p.) | Venlafaxine (8 mg·kg−1,i.p.) |
|---|---|---|---|---|
| Present study | David et al., 2003 | |||
| 5-HT/NE | 2.03 | 1.68 | 0.91 | 2.91 |