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Receptor binding experiments. Competition binding curves to [Dmt1]N/OFQ(1–13)-NH2 and standard ligands in membranes of CHO cells expressing NOP (top left panel), μ (top right panel), δ (bottom left panel) or κ (bottom right panel) opioid receptors. [3H]-UFP-101 was used as radioligand for the NOP and [3H]-DPN for classical opioid receptors. Data are the mean ± SEM of 3 separate experiments performed in duplicate.
