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Electrically stimulated guinea-pig ileum. Concentration-response curves to N/OFQ, dermorphin, and [Dmt1]N/OFQ(1–13)-NH2 (top left panel). Effects of naloxone and J-113397 vs N/OFQ (top right panel), dermorphin (bottom left panel), and [Dmt1]N/OFQ(1–13)-NH2 (bottom right panel). Data are the mean ± SEM of four separate experiments performed in duplicate.
