Table 1.
Subject characteristics.
| Early perimenopausal | Late perimenopausal | Early postmenopausal | |
|---|---|---|---|
| n | 16 | 12 | 11 |
| Age (years) | 48±1 | 50±l | 54±l*† |
| Peak work rate (W) | 30±2 | 34±3 | 29±1 |
| Resting FAD (cm) | 0.88±0.02 | 0.84±0.04 | 0.83±0.03 |
| 15 Watts FAD (cm) | 0.91±0.02 | 0.87±0.03 | 0.85±0.03 |
| Reproductive hormones | |||
| FSH (mIU·mL−1) | 12±2 | 74±6* | 84±10* |
| Estradiol (pg·mL−1) | 158±52 | 31±5* | 25±4* |
| LH (mIU·mL−1) | 9±2 | 41±5* | 50±6* |
| Cardiorespiratory fitness | |||
| V̇O2peak (mL·kg−1·min−1) | 35±2 | 36±2 | 29±l*† |
| V̇O2peak (mL·kg FFM−1·min−1) | 51±2 | 51±2 | 45±l*† |
| Physical activity | |||
| Light (%) | 8.6±0.6 | 8.2±0.5 | 8.3±0.6 |
| Moderate (%) | 7.9±0.8 | 7.7±0.4 | 8.0±0.8 |
| Vigorous (%) | 0.3±0.1 | 0.5±0.2 | 0.1±0.04 |
| Body composition | |||
| BMI (kg·m−2) | 23±1 | 23±1 | 25±1 |
| Body fat (%) | 29±2 | 29±2 | 34±1* |
| Abdominal fat (kg) | 1.3±0.1 | 1.4±0.1 | 1.9±0.3* |
| Metabolic factors | |||
| Glucose (mg·dL−1) | 87±l | 85±2 | 89±2 |
| Cholesterol (mg·dL−1) | 164±6 | 181±8 | 186±5 |
| LDL (mg·dL−1) | 86±4 | 97±7 | 104±6 |
| HDL (mg·dL−1) | 65±4 | 70±4 | 66±6 |
| Trig (mg·dL−1) | 67±7 | 68±6 | 78±8 |
| Arterial blood pressure | |||
| Resting SBP (mm Hg) | 114±3 | 110±4 | 118±3 |
| Resting DBP (mm Hg) | 66±3 | 66±2 | 73±3 |
Note: Values are mean ± standard error of the mean (SEM); n, number of subjects; FAD, femoral artery diameter; FSH, follicle-stimulating hormone; LH, lutcinizing hormone; V̇O2peak, peak oxygen uptake; FFM, fat-free mass; BMI, body mass index; LDL, low-density lipoprotein; HDL, high-density lipoprotein; Trig, triglycerides; SBP, systolic blood pressure; DBP, diastolic blood pressure.
An asterisk (*) indicates a significant difference from early perimenopausal, P < 0.05.
A dagger (†) indicates a significant difference between early postmenopausal and late perimenopausal, P < 0.05.